Research Interests

We are interested in understanding how memories are encoded, consolidated and recalled. Much of our work focuses on the hippocampus, one of the most well characterized and intensely studied regions of the mammalian brain and an ideal model system to test hypotheses linking memory and neural information representation. We combine in vivo electrophysiology and imaging with cutting-edge conditional genetics to address research questions at a high level of precision. Our ability to manipulate plasticity, synaptic transmission or neuronal excitability in a subregion or pathway specific manner and to characterize the consequences of those manipulations on the behavioral and physiological level allows us to study the dynamic routing and use of spatial information in the brain.

Media Coverage

研究成果

The big picture: mouse memory cells are about experience, not place

海馬記憶エングラムは経験の脳内表象へのインデックスである

Gene linked to intellectual ability affects memory replay in mice

知的障害モデルマウスの記憶障害は海馬リプレイの異常が一因

Deep-brain exploration with nanomaterial

近赤外線を用いて非侵襲的に神経細胞の活動を制御する

Stopping the brain's memory circuits from overheating

海馬CA2の活動が回路全体の活性化/抑制バランスを制御する

The brain clock that keeps memories ticking

海馬CA1の活動のタイミングはCA3が制御する

Meet the Team

Principal Investigator

Avatar

Thomas McHugh

Team Leader

Researchers

Avatar

Steven Middleton

Research Scientist

Avatar

Genki Minamisawa

Research Scientist

Avatar

Seiichiro Amemiya

Research Scientist

Avatar

Vladislav Sekulic

Research Scientist

Technical and Administrative Staff

Avatar

Arthur Huang

Technical Staff

Avatar

Denis Polygalov

Technical Staff

Avatar

Yuko Goto

Administrative Assistant

Students

Avatar

Hongshen He

PhD Candidate

Avatar

Linmeng He

Masters Student

Avatar

Xiyu Wang

Masters Student

Avatar

Hefei Guan

PhD Candidate

Visiting Scientists

Avatar

Kazumasa Z. Tanaka

JSPS, SPD, Assistant Professor (adjunct)

Avatar

Qi Zhang

University of Tsukuba

Avatar

Yasunori Hayashi

Kyoto University

Avatar

Yoshitake Sano

Tokyo University of Science

Alumni

Avatar

Adam Weitemier

Research Scientist

Avatar

Shuo Chen

Research Scientist

Avatar

Chinnakkaruppan Adaikkan

Visiting PhD Student

Avatar

Anupratap Tomar

Research Scientist

Avatar

Eriko Kamiki

Undergraduate Thesis Student

Avatar

Roman Boehringer

Technical Staff

Avatar

Yanqiu Tao

Undergraduate Thesis Student

Avatar

Marie Wintzer

Technical Staff

Avatar

Ming-Ching Chiang

PhD Student

Avatar

Lily Yu

Research Scientist

Avatar

Yuichi Makino

Research Scientist

All Publications

全論文リスト

Quickly discover relevant content by filtering publications.

Contact

お問い合わせ

Address

Laboratory for Circuit and Behavioral Physiology

Room 101b, Brain Science Neural Circuit Genetics Research Bldg. (C35)

RIKEN Center for Brain Science

2-1 Hirosawa, Wako-shi,

Saitama 351-0198, Japan

Contact Person

Yuko Goto - Administrative Assistant

E-mail: yuko.goto (at) riken.jp

Tel: +81-48-462-1111 ext. 6252 (from abroad)

Tel: 048-462-1111 ext. 6252 (from Japan)

Directions

For detailed information on transportation to Wako-shi station and accessing RIKEN Wako campus please refer to the following page of the Center for Brain Science website.

Find us on: Google Maps

Upon entering the C35 building pass through the entrance hall, turn right, enter green area, locate room 101b (Administrative Assistant) or 101k (Team Leader).

Floor map (1F) of the C35 building